Optimization of Herbal Dryer System Based on Smart Fuzzy and Internet of Thing (IOT)

The herbal medicine industry is currently growing rapidly with increasing public interest in herbal medicine in Indonesia. Medicinal plant dryers have been developed but are still using conventional methods. Proper drying method is very influential on the content of active ingredients found in plants. Each type of plant has a different response, there are some plants that are sensitive to direct sunlight and temperatures that are too high and some are not. This research will take part in producing an adaptive medicinal plant dryer product with the help of a microcontroller that will be used for the herbal medicine industry. In addition, with an intelligent system based on the Internet of Thing (IoT), this tool can be monitored and controlled remotely so that it can make it easier for users to know the current conditions of herbs that are being dried in order to get effective and efficient drying results. This research is expected to improve the quality of medicinal plants in accordance with the needs of the herbal medicine industry to produce good quality drugs according to the standards of Good Manufacturing Practices (GMP)

Synthesis, Characterization And Computational Studies Of Novel (E)-N-(3,4-Dimethoxybenzylidene)naphthalen-1-amine

Novel (E)-N-(3,4-dimethoxybenzylidene)naphthalen-1-amine (DBNA) ligand has been synthesized by refluxing 1-naphthylamine and 3,4-dimethoxybenzaldehyde in methanolic solution for 5-6 hours. The obtained compound was characterized by UV-Vis, FT-IR and 1H-NMR. All the spectral data confirmed the structure of the ligand

Synthesis, Characterization and Computational Studies of Novel (E)-N-(3,4-Dimethoxybenzylidene)naphthalen-1-amine

Novel (E)-N-(3,4-dimethoxybenzylidene)naphthalen-1-amine (DBNA) ligand has been synthesized by refluxing 1-naphthylamine and 3,4-dimethoxybenzaldehyde in methanolic solution for 5-6 hours. The obtained compound was characterized by UV-Vis, FT-IR and 1H-NMR. All the spectral data confirmed the structure of the ligand

Pembuatan Sediaan Beads Alginat dengan Metode Gelasi Ion yang Dapat Mengapung di Lambung

Conventional drug delivery systems have a shorter residence time in the stomach that causes less optimal drug absorption, the presence of food in the stomach also affects the absorption of the drug in the gastrointestinal tract so that it takes a drug that can stay and last longer in the stomach without being affected by the emptying process Stomach. In this study beads preparations are made that can stay and float so that lasts longer in the stomach. Alginate-containing beads are formulated by gelation method in which the alginate solution is dropped into a calcium chloride solution to form beads. The effects of oil type and alginate on morphological forms and buoyancy characteristics have been optimized. Beads containing alginate and paraffin can float on a gastric medium simulation for 240 minutes. The presence of paraffins can maintain the integrity and release of alginate beads during contact with the gastric medium. The SEM results describe the paraffin forming globules on the entire surface of the beads. Beads also show the ability to be able to float depending on the concentration of paraffin used

Budidaya Rumput Laut pada Kawasan Pantai Lampung Selatan

. Pemberdayaan masyarakat di Desa Lampung Selatan dalam  budidaya rumput laut merupakan upaya untuk meningkatkan pengetahuan masyarakat dalam budidaya rumput laut. Untuk itu kegiatan pengabdian ini bertujuan untuk: (1) Mengidentifikasi lokasi budidaya, (2) Menganalisis potensi kawasan budidaya, (3) Menganalisis kebermanfaatan dari pemberdayaan masyarakat, (4) Menganalisis keuntungan dan kerugian dari pemberdayaan masyarakat. Kegiatan pengabdian dilakukan dengan metode survei dengan melihat langsung kawasan sepanjang pantai mana yang berpotensi sebagai lahan budidaya serta melakukan analisis potensi kawasan budidaya yang cocok untuk budidaya rumput laut. Kegiatan pengabdian dapat : (1) Terciptanya kawasan lahan budidaya rumput laut di Desa, (2) Membentuk komunitas petani-petani rumput laut unggul yang sudah mendapat rekomendasi kepala desa untuk budidaya rumput laut, (3) Terciptanya desa binaan yang dibentuk oleh tim pengabdi dari Institut Teknologi Sumatera. Kegiatan pengabdian ini secara keseluruhan telah terlaksana dengan baik dengan beberapa data yang telah dikumpulkan, keberhasilan target pencarian lokasi potensial untuk budidaya rumput laut, ketercapaian tujuan budidaya, keberhasilan dalam budidaya rumput laut

Penambatan Molekul Senyawa Turunan Orizanol terhadap Enzim 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) Reduktase

Oryzanol has been reported to reduce serum total cholesterol (hypolipidemic agent) by inhibiting HMG-CoA reductase, an enzyme responsible for the metabolic pathway that produces cholesterol and isoprenoid. The purpose of this experiment is to determine the inhibition activity of oryzanol derivatives on HMG-CoA reductase by molecular docking. Four structure of oryzanol derivatives, Lanosteryl-ferulate, Brassicasteryl-ferulate, Lupeol-ferulate, and Cholesteryl-ferulate were used as ligands for molecular docking. The HMG-CoA reductase structure was obtained from protein data bank and the study was performed using AutoDock Tools as a molecular docking software. All oryzanol derivatives show binding affinity against HMG-CoA reductase. Lupeol-ferulate was predicted to be the best inhibitory activity against HMG-CoA reductase because of molecular docking